When a man is sexually aroused, the body releases nitric oxide, which activates an enzyme called guanylate cyclase. This enzyme, in turn, leads to an increase in cyclic guanosine monophosphate (cGMP) levels. Elevated cGMP levels relax the smooth muscles in the penile arteries, allowing increased blood flow to the erectile tissues, leading to an erection.
However, in individuals with ED, the enzyme PDE-5 breaks down cGMP, hindering the normal erectile response. Fildena CT 100 mg inhibits PDE-5, allowing cGMP to accumulate, leading to improved blood flow and a more robust erection.
